Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL1412484 | 0.98 | TDP1 (0.48) | TDP1MAPK1HSD17B10TSHRLMNA | |
| Ethylene Glycol SCHEMBL3058484 | 0.98 | TDP1 (0.48) | TDP1MAPK1HSD17B10TSHRLMNA | |
| Propylene Glycol SCHEMBL412141 | 0.95 | TDP1 (0.53) | TDP1MAPK1HSD17B10TSHRLMNA | |
| Ethylene Glycol SCHEMBL3064316 | 0.93 | TDP1 (0.50) | TDP1MAPK1HSD17B10 | |
| Ethylene Glycol SCHEMBL11072979 | 0.93 | TDP1 (0.50) | TDP1MAPK1HSD17B10 | |
| SCHEMBL23248656 | 0.93 | — | — | |
| SCHEMBL7612087 | 0.93 | TDP1 (0.52) | TDP1MAPK1HSD17B10TSHRLMNA | |
| SCHEMBL15111 | 0.93 | — | — | |
| SCHEMBL8747551 | 0.93 | — | — | |
| SCHEMBL16542024 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111290225-A | Toner and image forming apparatus | 佳能株式会社 | 2020-06-16 | — | — | CN | disclosed |