Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28420055 | 0.92 | SMN1; SMN2 (0.40) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL27486503 | 0.86 | ALDH1A1 (0.54) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL4118014 | 0.83 | ALDH1A1 (0.41) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL30554011 | 0.83 | ALDH1A1 (0.41) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL30554028 | 0.83 | JMJD6 (0.42) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL1838525 | 0.82 | TNF (0.47) | — | |
| SCHEMBL28413273 | 0.81 | SMN1; SMN2 (0.40) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL1422820 | 0.81 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL30554005 | 0.80 | JMJD6 (0.40) | CYP1A2ALDH1A1KMT2AHPGDJMJD6 | |
| SCHEMBL30554008 | 0.80 | JMJD6 (0.40) | CYP1A2ALDH1A1KMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187218-B | Application of 1-substituted-1H-imidazole-2-carboxylic acid compound in preparation of metal beta-lactamase inhibitor | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-B | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-A | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2020-06-09 | — | — | CN | disclosed |
| CN-111187218-A | Application of 1-substituted-1H-imidazole-2-carboxylic acid compounds in preparation of metal β -lactamase inhibitor | 四川大学 | 2020-05-22 | — | — | CN | disclosed |