SCHEMBL28419554

SCHEMBL28419554

Cc1cc2c(c(-c3ccc(Nc4ccc(-c5ccccc5)cc4)cc3)c1C)Cc1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 1/20 0.36
CYP1A2 P05177 2/20 0.35
ADRA2A P08913 1/20 0.35
MAOA P21397 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35
SLC6A4 P31645 1/20 0.35
HTR2B P41595 1/20 0.35
KDR P35968 3/20 0.34
HIF1A Q16665 2/20 0.34
PGR P06401 1/20 0.34
CYP3A4 P08684 1/20 0.33
SQOR Q9Y6N5 1/20 0.33
CNR1 P21554 1/20 0.33
STK10 O94804 1/20 0.33
SLK Q9H2G2 1/20 0.33
HPGD P15428 2/20 0.33
PTGER4 P35408 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30103626 0.89 PGR (0.40) CYP1A2MAOAKDRPGRCYP3A4
SCHEMBL25217211 0.89 PGR (0.40) CYP1A2MAOAKDRPGRCYP3A4
SCHEMBL30332886 0.83 PGR (0.37) CYP1A2MAOASLC6A2SLC6A4KDR
SCHEMBL30021517 0.81 PGR (0.38) MAOAKDRPGRSQORHPGD
SCHEMBL6256393 0.80 PGR (0.43) CYP1A2ADRA2AMAOASLC6A2HTR2C
SCHEMBL30021919 0.80 PGR (0.37) MAOAKDRPGRSQORHPGD
SCHEMBL28173902 0.79 PGR (0.40) MAOAKDRPGRSQORHPGD
SCHEMBL29177673 0.79 PGR (0.42) CYP1A2ADRA2AMAOASLC6A2HTR2C
SCHEMBL30103698 0.79 PGR (0.42) CYP1A2ADRA2AMAOASLC6A2HTR2C
SCHEMBL28006587 0.78 KDR (0.39) KDRPGRSQORHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111213251-B organic light emitting diode 株式会社LG化学 2023-09-29 CN disclosed
CN-111213251-A Organic light emitting diode 株式会社LG化学 2020-05-29 CN disclosed