Cholesterol

Cholesterol

SCHEMBL28419656

CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C.CCCCCCCCCCCCCCCCCCN

nearest known ligand 0.83

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ OSBP P22059 6/20 0.83
▸ RORC P51449 5/20 0.83
▸ OSBP2 Q969R2 3/20 0.83
▸ USP2 O75604 1/20 0.83
▸ LMNA P02545 1/20 0.83
▸ ABCB1 P08183 1/20 0.83
▸ CYP46A1 Q9Y6A2 1/20 0.83
▸ GRIN1 Q05586 5/20 0.71
▸ GRIN2A Q12879 5/20 0.71
▸ NR1H3 Q13133 5/20 0.71
▸ CRYAB P02511 1/20 0.68
▸ HMGCR P04035 1/20 0.68
▸ ITGB3 P05106 1/20 0.68
▸ ITGAV P06756 1/20 0.68
▸ SREBF2 Q12772 1/20 0.68
▸ NPC1L1 Q9UHC9 1/20 0.68
▸ GRIN2B Q13224 4/20 0.67
▸ TSHR P16473 1/20 0.66
▸ TDP1 Q9NUW8 1/20 0.66
▸ F2 P00734 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cholesterol SCHEMBL3209056 1.00 OSBP (0.83) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL3209061 1.00 OSBP (0.83) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL4661902 1.00 OSBP (0.83) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL4661901 1.00 OSBP (0.83) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL28077325 0.98 OSBP (0.83) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL27651839 0.97 OSBP (0.78) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL28097544 0.97 OSBP (0.89) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL27624441 0.96 OSBP (0.91) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL27968992 0.95 OSBP (0.93) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL18049020 0.93 OSBP (0.93) OSBPRORCOSBP2USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117715659-A Nucleic acid vector compositions SISAF有限公司 2024-03-15 — — CN disclosed
CN-111296426-B Preparation method and application of nano pesticide formulation using non-phospholipid liposome as carrier 大连理工大学 2021-09-24 — — CN disclosed
CN-111296426-A Preparation method and application of nano pesticide formulation using non-phospholipid liposome as carrier 大连理工大学 2020-06-19 — — CN disclosed
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