Sebacic Acid

Sebacic Acid

SCHEMBL28420104

CN(C)N1C=CC=CC1.O=C(O)CCCCCCCCC(=O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.39
LMNA P02545 2/20 0.39
NFKB1 P19838 1/20 0.39
PMP22 Q01453 1/20 0.39
GPR84 Q9NQS5 7/20 0.37
PPARG P37231 7/20 0.37
PPARD Q03181 7/20 0.37
PPARA Q07869 7/20 0.37
HDAC11 Q96DB2 5/20 0.37
ALDH1A1 P00352 4/20 0.37
PTPN1 P18031 3/20 0.37
TLR2 O60603 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MEN1 O00255 2/20 0.37
FABP4 P15090 2/20 0.37
ALOX15 P16050 2/20 0.37
KMT2A Q03164 2/20 0.37
SLC22A6 Q4U2R8 1/20 0.37
SLC22A8 Q8TCC7 1/20 0.37
ESR1 P03372 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL28426972 0.98 LMNA (0.37) TSHRLMNANFKB1PMP22GPR84
Octanoic Acid SCHEMBL28420102 0.94 PPARG (0.49) TSHRLMNAGPR84PPARGPPARD
Decanoic Acid SCHEMBL28894552 0.94 PPARG (0.49) TSHRLMNAGPR84PPARGPPARD
Hexanoate SCHEMBL28425838 0.92 AKR1B1 (0.47) TSHRLMNAGPR84PPARGPPARD
Succinic Acid SCHEMBL28427917 0.92 PHF8 (0.34) LMNA
Valeric Acid SCHEMBL28420103 0.91 AKR1B1 (0.40) TSHRLMNAGPR84PPARGPPARD
Butyric Acid SCHEMBL28417232 0.87 FFAR3 (0.42) LMNAPPARGPPARDPPARAALDH1A1
Propionic Acid SCHEMBL28425835 0.85 FFAR3 (0.36)
Oxalic Acid SCHEMBL28427918 0.83
Acetic Acid SCHEMBL28429931 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111393321-A Preparation method of 1-cyano-2-propenyl acetate 山东新和成氨基酸有限公司 2020-07-10 CN claimed
CN-111393321-A Preparation method of 1-cyano-2-propenyl acetate 山东新和成氨基酸有限公司 2020-07-10 CN disclosed