Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28851024 | 0.88 | KDM4E (0.47) | KDM4EMPOCYP1A2CYP3A4ADORA3 | |
| SCHEMBL29123005 | 0.85 | DDB1 (0.43) | KDM4ECYP1A2CYP3A4NPC1RAB9A | |
| SCHEMBL2998832 | 0.74 | KDM4E (0.64) | KDM4EMPOCYP1A2CYP3A4ADORA3 | |
| SCHEMBL2989555 | 0.73 | CYP1A2 (0.60) | KDM4EMPOCYP1A2CYP3A4ADORA3 | |
| SCHEMBL10796248 | 0.73 | DDB1 (0.46) | KDM4ECYP1A2CYP3A4NPC1RAB9A | |
| SCHEMBL1543956 | 0.73 | KDM4E (0.55) | KDM4EMPOCYP1A2CYP3A4ADORA3 | |
| SCHEMBL30637340 | 0.73 | KDM4E (0.55) | KDM4EMPOCYP1A2CYP3A4ADORA3 | |
| SCHEMBL2993048 | 0.71 | KDM4E (0.49) | KDM4EMPOCYP1A2CYP3A4ADORA3 | |
| SCHEMBL11155559 | 0.71 | KDM4E (0.49) | KDM4EMPOCYP1A2CYP3A4ADORA3 | |
| SCHEMBL1417739 | 0.71 | GABRP (0.63) | KDM4EMPOCYP1A2CYP3A4ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115629139-A | Method for determining content of impurities in propylthioisoniazid by using HPLC (high performance liquid chromatography) | 江苏慈星药业有限公司 | 2023-01-20 | — | — | CN | claimed |
| CN-115616113-A | Method for determining impurity content in clozapine raw material medicine by using HPLC | 江苏慈星药业有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-215232183-U | A device that is used for propylthio isoniazid amine crude aftertreatment | 江苏慈星药业有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-117597138-A | Pharmaceutical compositions comprising micrococcum compounds and methods of preparing micrococcum compounds | A&J科学有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-113267584-B | HPLC related substance analysis method for medicinal substance | 北京亚宝生物药业有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-113358792-B | HPLC content analysis method of medicinal substance | 北京亚宝生物药业有限公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-115629139-A | Method for determining content of impurities in propylthioisoniazid by using HPLC (high performance liquid chromatography) | 江苏慈星药业有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-115629139-A | Method for determining content of impurities in propylthioisoniazid by using HPLC (high performance liquid chromatography) | 江苏慈星药业有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-115629139-A | Method for determining content of impurities in propylthioisoniazid by using HPLC (high performance liquid chromatography) | 江苏慈星药业有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-114981265-A | Compound (I) | CTXT私人有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-113975274-A | Cyclofused thiazoline 2-pyridones, method for the production thereof and use thereof for treating and/or preventing tuberculosis | 快尔生物技术公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-109069492-B | Cyclofused thiazoline 2-pyridones, method for the production thereof and use thereof for treating and/or preventing tuberculosis | 快尔生物技术公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-113380362-A | Chronic disease supervision method, platform, system, electronic equipment and storage medium | 安徽科大讯飞医疗信息技术有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-113358792-A | HPLC content analysis method of medicinal substance | 北京亚宝生物药业有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-113267584-A | HPLC related substance analysis method for medicinal substance | 北京亚宝生物药业有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-111675635-A | Compounds and methods for treating infections | 尼奥酷里私人有限公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-111630036-A | Oxoacridinylacetic acid derivatives and methods of use thereof | 西利康斯瓦特股份有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-111246848-A | Cyclofused thiazolo 2-pyridones in combination with antitubercular agents | 快尔生物技术公司 | 2020-06-05 | — | — | CN | disclosed |