Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460752 | 0.85 | POLB (0.73) | POLBCYP2D6SNCAKMT2AMEN1 | |
| SCHEMBL460751 | 0.85 | POLB (0.73) | POLBCYP2D6SNCAKMT2AMEN1 | |
| SCHEMBL11062547 | 0.84 | POLB (0.71) | POLBCYP2D6SNCAKMT2AMEN1 | |
| SCHEMBL9479439 | 0.79 | SNCA (0.73) | POLBCYP2D6SNCAMAPK13MAPK12 | |
| SCHEMBL315795 | 0.79 | SNCA (0.73) | POLBCYP2D6SNCAMAPK13MAPK12 | |
| Diphenylamine SCHEMBL28417536 | 0.74 | TSHR (0.73) | POLBCYP2D6SNCAMAPK13MAPK12 | |
| SCHEMBL29448172 | 0.73 | POLB (0.58) | POLBCYP2D6SNCAKMT2AMEN1 | |
| SCHEMBL146552 | 0.73 | POLB (0.58) | POLBCYP2D6SNCAKMT2AMEN1 | |
| SCHEMBL109593 | 0.73 | POLB (0.58) | POLBCYP2D6SNCAKMT2AMEN1 | |
| SCHEMBL31156521 | 0.72 | MAPK13 (0.57) | SNCAMAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108795137-B | Modified temperature sensing agent and reversible temperature indicating coating as well as preparation method and product thereof | 广州茵诺威化工有限公司 | 2020-06-12 | — | — | CN | disclosed |