SCHEMBL28420644

SCHEMBL28420644

Fc1cc(F)c(Br)c(Br)c1F

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.35
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA4 P22748 2/20 0.35
CA12 O43570 1/20 0.35
CA7 P43166 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
KDM1A O60341 2/20 0.34
KDM1B Q8NB78 1/20 0.34
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439846 0.87 CA1 (0.38) CA1CA2CA4CA12CA7
SCHEMBL6553501 0.84 CA1 (0.36) CA1CA2CA4CA12CA7
Bromide SCHEMBL10982443 0.81 CA1 (0.35) CA1CA2CA4CA12CA7
Ethylene SCHEMBL27505929 0.81 CA1 (0.35) CA1CA2CA4CA12CA7
Bromide SCHEMBL10982440 0.81 CA1 (0.35) CA1CA2CA4CA12CA7
SCHEMBL2933659 0.81 CA1 (0.35) AKR1B1CA1CA2CA4CA12
SCHEMBL31258564 0.81 CA1 (0.35) AKR1B1CA1CA2CA4CA12
SCHEMBL29387130 0.80 KDM1A (0.37) AKR1B1CA1CA2CA4CA12
Cyanide SCHEMBL21633856 0.79 CA1 (0.33) CA1CA2CA4CA12CA7
SCHEMBL1269773 0.75 CA1 (0.39) CA1CA2CA4CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108276445-B Thermal excitation delayed fluorescence main body material and preparation and application thereof 黑龙江大学 2020-03-31 CN claimed
CN-108276445-B Thermal excitation delayed fluorescence main body material and preparation and application thereof 黑龙江大学 2020-03-31 CN disclosed
CN-108276447-B Thermally-excited delayed fluorescence guest material and preparation and application thereof 黑龙江大学 2020-03-31 CN disclosed