Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18561873 | 1.00 | TSHR (0.54) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL18561874 | 1.00 | TSHR (0.54) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL27471330 | 0.86 | TSHR (0.50) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL28851713 | 0.84 | TSHR (0.36) | TSHRTDP1CYP3A4ATML3MBTL1 | |
| SCHEMBL7783972 | 0.83 | TDP1 (0.64) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL2492438 | 0.83 | TSHR (0.60) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL20640432 | 0.81 | TDP1 (0.34) | TSHRTDP1 | |
| SCHEMBL28006363 | 0.81 | TSHR (0.53) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL1547587 | 0.81 | TSHR (0.53) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL8909059 | 0.80 | TSHR (0.51) | TSHRTDP1SMN1; SMN2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356762-A | Lipase variants and microcapsule compositions comprising such lipase variants | 诺维信公司 | 2020-06-30 | — | — | CN | disclosed |