SCHEMBL1547587

SCHEMBL1547587

C=CCOC(=O)CCC(N)CC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.53
TDP1 Q9NUW8 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.38
PKM P14618 1/20 0.38
ALDH1A1 P00352 4/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
CYP3A4 P08684 2/20 0.33
ATM Q13315 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
EPHX2 P34913 1/20 0.32
HSD17B10 Q99714 2/20 0.32
KMT2A Q03164 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
BLM P54132 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28422713 0.81 TSHR (0.54) TSHRTDP1SMN1; SMN2PKMALDH1A1
SCHEMBL18561873 0.81 TSHR (0.54) TSHRTDP1SMN1; SMN2PKMALDH1A1
SCHEMBL18561874 0.81 TSHR (0.54) TSHRTDP1SMN1; SMN2PKMALDH1A1
SCHEMBL27424409 0.80 CYP1A2 (0.50) TSHRTDP1ALDH1A1GAAL3MBTL1
SCHEMBL176227 0.79 TSHR (0.47) TSHRTDP1SMN1; SMN2PKMALDH1A1
SCHEMBL3968417 0.79 TSHR (0.47) TSHRTDP1SMN1; SMN2PKMALDH1A1
SCHEMBL176229 0.79 TSHR (0.47) TSHRTDP1SMN1; SMN2PKMALDH1A1
SCHEMBL7783972 0.78 TDP1 (0.64) TSHRTDP1SMN1; SMN2PKMALDH1A1
SCHEMBL14667033 0.78 TSHR (0.47) TSHRTDP1SMN1; SMN2PKMALDH1A1
SCHEMBL11599284 0.78 TSHR (0.51) TSHRTDP1SMN1; SMN2PKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101019024-B Taxol immunoassay method SALADAX BIOMEDICAL INC 2013-08-21 CN disclosed
EP-2315026-A2 Taxol immunoassay Saladax Biomedical Inc. (US) 2011-04-27 EP disclosed
EP-2237035-A2 Taxol derivatives for taxol immunoassay Saladax Biomedical Inc. (US) 2010-10-06 EP disclosed
EP-1771732-B1 TAXOL IMMUNOASSAY SALADAX BIOMEDICAL INC (US) 2010-07-14 EP disclosed
US-20090221786-A1 Taxol immunoassay SHANGHAI FOSUN PHARMACEUTICAL (GROUP) CO., LTD. (CN) 2009-09-03 US disclosed
EP-1771732-A4 TAXOL IMMUNOASSAY SALADAX BIOMEDICAL INC (US) 2008-08-27 EP disclosed
CN-101019024-A Taxol immunoassay method SALADAX BIOMEDICAL INC (US) 2007-08-15 CN disclosed
US-20070092922-A1 Taxol immunoassay SALADAX BIOMEDICAL INC. 2007-04-26 US disclosed
EP-1771732-A2 TAXOL IMMUNOASSAY Saladax Biomedical Inc. (US) 2007-04-11 EP disclosed
US-7175993-B2 Taxol immunoassay SALADAX BIOMEDICAL, INC. (US) 2007-02-13 US disclosed
US-20060099665-A1 Taxol immunoassay SALADAX BIOMEDICAL INC. 2006-05-11 US disclosed
WO-2006015098-A2 TAXOL IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2006-02-09 WO disclosed
US-20060024769-A1 Taxol immunoassay SALADAX BIOMEDICAL INC. 2006-02-02 US disclosed
US-20060024768-A1 Taxol immunoassay SALADAX BIOMEDICAL, INC. 2006-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221786-A1 Taxol immunoassay TUBB6, TUBA1C, TUBB1 TSHR 3736/4885TDP1 718/4885SMN1; SMN2 1467/4885
US-20070092922-A1 Taxol immunoassay TUBB6, TUBA1C, TUBB1 TSHR 3736/4885TDP1 718/4885SMN1; SMN2 1467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.