Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423296 | 0.87 | KCNH3 (0.49) | RAD52KMT2APOLBAPPKDM4E | |
| SCHEMBL30092584 | 0.77 | KMT2A (0.51) | RAD52KMT2APOLBHSD17B10BACE1 | |
| SCHEMBL30353808 | 0.77 | KMT2A (0.51) | RAD52KMT2APOLBHSD17B10BACE1 | |
| SCHEMBL8053546 | 0.75 | HDAC6 (0.64) | KMT2APOLBBACE1KDM4EALDH1A1 | |
| SCHEMBL4571036 | 0.74 | HSD17B10 (0.71) | KMT2APOLBHSD17B10BACE1KDM4E | |
| SCHEMBL30464743 | 0.74 | HSD17B10 (0.71) | KMT2APOLBHSD17B10BACE1KDM4E | |
| SCHEMBL17432180 | 0.74 | RAD52 (0.65) | RAD52KMT2APOLBAPPKDM4E | |
| SCHEMBL28418261 | 0.73 | MAPT (0.50) | KMT2APOLBHSD17B10KDM4ETP53 | |
| SCHEMBL3298289 | 0.72 | KCNH3 (0.73) | RAD52KMT2APOLBAPPKDM4E | |
| SCHEMBL11583706 | 0.72 | MAPT (0.55) | KMT2AKDM4ERAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303057-B | Phenazine derivative with nitrogen-containing side chain and preparation method and application thereof | 南通大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-111303057-A | Phenazine derivative with nitrogen-containing side chain and preparation method and application thereof | 南通大学 | 2020-06-19 | — | — | CN | disclosed |