SCHEMBL28423744

SCHEMBL28423744

CCCCCCCCCC[Si](C)(C)OC(C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
DNM1 Q05193 2/20 0.32
TRPM8 Q7Z2W7 4/20 0.31
OPRM1 P35372 1/20 0.31
EPHX1 P07099 1/20 0.31
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26730988 1.00 LMNA (0.36) LMNATSHRTHRBDNM1TRPM8
SCHEMBL28423860 1.00 LMNA (0.36) LMNATSHRTHRBDNM1TRPM8
SCHEMBL28421155 1.00 LMNA (0.36) LMNATSHRTHRBDNM1TRPM8
SCHEMBL23093225 0.91 LMNA (0.30) LMNA
SCHEMBL13430610 0.91
SCHEMBL28416449 0.89 LMNA (0.34) LMNA
SCHEMBL28425904 0.89 LMNA (0.34) LMNA
SCHEMBL28423934 0.89 LMNA (0.34) LMNA
SCHEMBL28423876 0.89 LMNA (0.34) LMNA
SCHEMBL28423818 0.89 LMNA (0.34) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233916-A Long carbon chain sulfur-containing silane coupling agent, and preparation method and application thereof 南京曙光精细化工有限公司 2020-06-05 CN disclosed