Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 4/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 4/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 4/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL28424292 | 1.00 | GSR (0.50) | GSRGNAI3GNAO1GNAI1ARG1 | |
| Lysine SCHEMBL28425317 | 0.94 | GSR (0.49) | GSRGNAI3GNAO1GNAI1ARG1 | |
| Lysine SCHEMBL28425319 | 0.94 | GSR (0.49) | GSRGNAI3GNAO1GNAI1ARG1 | |
| Lysine SCHEMBL28698757 | 0.94 | GSR (0.54) | GSRARG1NOS1DPP8DPP9 | |
| Lysine SCHEMBL28698754 | 0.94 | GSR (0.54) | GSRARG1NOS1DPP8DPP9 | |
| Lysine SCHEMBL28421226 | 0.90 | GSR (0.53) | GSRGNAI3GNAO1GNAI1ARG1 | |
| Lysine SCHEMBL28421228 | 0.90 | GSR (0.53) | GSRGNAI3GNAO1GNAI1ARG1 | |
| Lysine SCHEMBL16390576 | 0.81 | GNAI3 (0.41) | GNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL28707815 | 0.80 | GSR (0.50) | GSRGNAI3GNAO1GNAI1ARG1 | |
| D-Glutamate SCHEMBL26692350 | 0.80 | SLC1A2 (0.45) | GSRGRIK1GRIK2SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111019111-B | Ionic liquid catalyst for synthesizing bio-based polycarbonate and method for synthesizing bio-based polycarbonate | 中国科学院过程工程研究所 | 2021-03-30 | — | — | CN | disclosed |
| CN-111019111-A | Ionic liquid catalyst for synthesizing bio-based polycarbonate and method for synthesizing bio-based polycarbonate | 中国科学院过程工程研究所 | 2020-04-17 | — | — | CN | disclosed |