Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SRSF6 | Q13247 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423956 | 1.00 | ADRB2 (0.41) | ADRB2ADRB1ADRB3SLC6A2ADRA1D | |
| SCHEMBL14643021 | 0.90 | ADRB2 (0.45) | ADRB2ADRB1ADRB3 | |
| SCHEMBL19770230 | 0.89 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL1313420 | 0.86 | ADRB2 (0.35) | ADRB2ADRB1ADRB3 | |
| SCHEMBL18016240 | 0.85 | ADRB2 (0.40) | ADRB2ADRB1SLC6A2ADRA1DHTR2A | |
| SCHEMBL18918591 | 0.85 | ADRB2 (0.45) | ADRB2ADRB1ADRB3 | |
| SCHEMBL18918588 | 0.85 | ADRB2 (0.45) | ADRB2ADRB1ADRB3 | |
| SCHEMBL18259960 | 0.85 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL18259959 | 0.85 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL17979058 | 0.85 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574529-A | Muscarinic receptor M3 antagonists and β 2-adrenergic receptor agonist bridged ring derivatives | 四川海思科制药有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-111423434-A | Carbonamide derivative and preparation method thereof | 四川海思科制药有限公司 | 2020-07-17 | — | — | CN | disclosed |