Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815909 | 0.98 | GBA1 (0.34) | GBA1 | |
| Bromide SCHEMBL30913592 | 0.88 | — | — | |
| Bromide SCHEMBL1657078 | 0.88 | — | — | |
| Bromide SCHEMBL30913591 | 0.88 | — | — | |
| Bromide SCHEMBL1657102 | 0.87 | GBA1 (0.37) | GBA1 | |
| SCHEMBL3816759 | 0.85 | AGL (0.30) | — | |
| SCHEMBL349593 | 0.85 | — | — | |
| SCHEMBL3820681 | 0.84 | ALDH1A1 (0.36) | GBA1 | |
| SCHEMBL3818903 | 0.84 | GBA1 (0.38) | GBA1 | |
| SCHEMBL3814707 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107537576-B | Immobilized catalyst of silane coupling molecular sieve and double-salt ionic liquid | 沈阳工业大学 | 2020-07-07 | — | — | CN | disclosed |