Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.64 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.64 |
| ▸ | EHMT2 | Q96KQ7 | 13/20 | 0.64 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.57 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.52 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424447 | 1.00 | TLR9 (0.64) | TLR9TLR7EHMT2DNMT3AKMT5A | |
| SCHEMBL20602870 | 0.91 | EHMT2 (0.69) | EHMT2DNMT3ANSD2NSD3EHMT1 | |
| SCHEMBL20602871 | 0.91 | EHMT2 (0.69) | EHMT2DNMT3ANSD2NSD3EHMT1 | |
| SCHEMBL20621265 | 0.91 | KMT5A (0.62) | EHMT2KMT5ANSD2EHMT1 | |
| SCHEMBL29453059 | 0.91 | KMT5A (0.62) | EHMT2KMT5ANSD2EHMT1 | |
| SCHEMBL22084192 | 0.88 | KMT5A (0.55) | EHMT2KMT5ANSD2EHMT1KDM1A | |
| SCHEMBL29453051 | 0.88 | KMT5A (0.55) | EHMT2KMT5ANSD2EHMT1KDM1A | |
| SCHEMBL20620934 | 0.88 | KMT5A (0.55) | EHMT2KMT5ANSD2EHMT1KDM1A | |
| SCHEMBL22026561 | 0.85 | KMT5A (0.55) | TLR9EHMT2DNMT3AKMT5ANSD2 | |
| SCHEMBL22084004 | 0.84 | EHMT2 (0.81) | EHMT2DNMT3ANSD2NSD3EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111432820-A | Heterochromatin gene repression inhibitors | 北卡罗来纳大学教堂山分校 | 2020-07-17 | — | — | CN | disclosed |