Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 12/20 | 0.52 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.51 |
| ▸ | CCR4 | P51679 | 5/20 | 0.49 |
| ▸ | WHR1 | P49842 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22084192 | 1.00 | KMT5A (0.55) | KMT5ANSD2EHMT2EHMT1CCR4 | |
| SCHEMBL20620934 | 1.00 | KMT5A (0.55) | KMT5ANSD2EHMT2EHMT1CCR4 | |
| SCHEMBL20621265 | 0.92 | KMT5A (0.62) | KMT5ANSD2EHMT2EHMT1CCR4 | |
| SCHEMBL29453059 | 0.92 | KMT5A (0.62) | KMT5ANSD2EHMT2EHMT1CCR4 | |
| SCHEMBL22026560 | 0.90 | EHMT2 (0.58) | EHMT2EHMT1CCR4WHR1 | |
| SCHEMBL20602882 | 0.90 | EHMT2 (0.58) | EHMT2EHMT1CCR4WHR1 | |
| SCHEMBL20620893 | 0.90 | NSD2 (0.54) | KMT5ANSD2EHMT2WHR1KDM1A | |
| SCHEMBL20620895 | 0.90 | NSD2 (0.54) | KMT5ANSD2EHMT2WHR1KDM1A | |
| SCHEMBL28424447 | 0.88 | TLR9 (0.64) | KMT5ANSD2EHMT2EHMT1KDM1A | |
| SCHEMBL28424449 | 0.88 | TLR9 (0.64) | KMT5ANSD2EHMT2EHMT1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254654-B2 | Heterochromatin gene repression inhibitors | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11254654-B2 | Heterochromatin gene repression inhibitors | CTCF, EHMT2, CBX3 | KMT5A 194/4885NSD2 163/4885EHMT2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.