Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430804 | 0.96 | TLR9 (0.56) | TLR9TLR7DRD3HRH3XDH | |
| SCHEMBL28432073 | 0.94 | PRKDC (0.53) | TLR9TLR7DRD3HRH3XDH | |
| SCHEMBL28426373 | 0.92 | TLR9 (0.58) | TLR9TLR7DRD3HRH3XDH | |
| SCHEMBL28427282 | 0.91 | TLR9 (0.71) | TLR9TLR7XDH | |
| SCHEMBL28426374 | 0.90 | TLR9 (0.71) | TLR9TLR7HRH3XDHHRH4 | |
| SCHEMBL28432877 | 0.88 | TLR9 (0.57) | TLR9TLR7DRD3HRH3XDH | |
| SCHEMBL28431993 | 0.87 | TLR9 (0.56) | TLR9TLR7HRH3SIGMAR1 | |
| SCHEMBL28894159 | 0.87 | TLR9 (0.56) | TLR9TLR7DRD3HRH3XDH | |
| SCHEMBL28435805 | 0.86 | TLR9 (0.55) | TLR9TLR7SIGMAR1 | |
| SCHEMBL28430198 | 0.85 | HRH3 (0.57) | TLR9TLR7DRD3HRH3XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285819-A | Benzoxazole compound and application thereof | 江苏恩华药业股份有限公司 | 2020-06-16 | — | — | CN | disclosed |