Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CCR4 | P51679 | 3/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424607 | 0.94 | TLR9 (0.60) | TLR9TLR7SIGMAR1DRD3HRH3 | |
| SCHEMBL28430804 | 0.93 | TLR9 (0.56) | TLR9TLR7SIGMAR1DRD3HRH3 | |
| SCHEMBL28426373 | 0.85 | TLR9 (0.58) | TLR9TLR7DRD3HRH3XDH | |
| SCHEMBL28427282 | 0.85 | TLR9 (0.71) | TLR9TLR7MAOBXDHKDM4E | |
| SCHEMBL28426374 | 0.84 | TLR9 (0.71) | TLR9TLR7MAOBHRH3XDH | |
| SCHEMBL28432877 | 0.82 | TLR9 (0.57) | TLR9TLR7DRD3HRH3XDH | |
| SCHEMBL28431974 | 0.82 | KDM4E (0.62) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28894159 | 0.81 | TLR9 (0.56) | TLR9TLR7MAOBDRD3HRH3 | |
| SCHEMBL28431993 | 0.81 | TLR9 (0.56) | TLR9TLR7SIGMAR1MAOBHRH3 | |
| SCHEMBL28435805 | 0.80 | TLR9 (0.55) | TLR9TLR7SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285819-A | Benzoxazole compound and application thereof | 江苏恩华药业股份有限公司 | 2020-06-16 | — | — | CN | disclosed |