SCHEMBL28424892

SCHEMBL28424892

C#Cc1ccc(C(=O)N2CCC[C@H]2C(=O)N2CCC[C@H]2C(=O)OC)cc1

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
PDK2 Q15119 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
NPC1 O15118 1/20 0.46
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28426712 0.95 ALDH1A1 (0.51) ALDH1A1PDK2L3MBTL1NPC1KMT2A
SCHEMBL28972159 0.85 PDK2 (0.43) ALDH1A1PDK2L3MBTL1NPC1KMT2A
SCHEMBL27995348 0.82 ALDH1A1 (0.60) ALDH1A1L3MBTL1KMT2ANPSR1
SCHEMBL10721062 0.81 KMT2A (0.60) ALDH1A1PDK2L3MBTL1NPC1KMT2A
SCHEMBL28972225 0.80 ALDH1A1 (0.62) ALDH1A1L3MBTL1NPSR1
SCHEMBL18767537 0.79 ALDH1A1 (0.57) ALDH1A1PDK2L3MBTL1NPC1KMT2A
SCHEMBL6172949 0.79 NPC1 (0.53) ALDH1A1PDK2L3MBTL1NPC1KMT2A
SCHEMBL28514213 0.79 ALDH1A1 (0.55) ALDH1A1PDK2L3MBTL1NPC1KMT2A
SCHEMBL24435015 0.79 KMT2A (0.59) ALDH1A1PDK2NPC1KMT2A
SCHEMBL1762519 0.79 KMT2A (0.59) ALDH1A1PDK2NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111410812-B Preparation method of spiral polyphenylacetylene/silicon-based hybrid porous material 哈尔滨工程大学 2023-03-21 CN disclosed
CN-111410812-A Preparation method of novel spiral polyphenylacetylene/silicon-based hybrid porous material 哈尔滨工程大学 2020-07-14 CN disclosed