Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27415306 | 0.80 | ALDH1A1 (0.40) | TSHRSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL27419466 | 0.78 | TSHR (0.46) | TSHRSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3330970 | 0.78 | SMN1; SMN2 (0.47) | TSHRSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL27411495 | 0.77 | GAA (0.36) | TSHRSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL12877431 | 0.76 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10157247 | 0.75 | SMN1; SMN2 (0.49) | TSHRSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL31442708 | 0.74 | TSHR (0.60) | TSHRSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL19242432 | 0.72 | CA12 (0.50) | TSHRSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL23574981 | 0.71 | FABP3 (0.52) | TSHRSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL28418271 | 0.71 | PARP1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111205223-B | Quinoline derivatives, preparation method and application thereof | 山东省联合农药工业有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-111205223-A | Quinoline derivatives, preparation method and application thereof | 山东省联合农药工业有限公司 | 2020-05-29 | — | — | CN | disclosed |