Phosphoric Acid

Phosphoric Acid

SCHEMBL28426124

CCCNCCC.N.O=P(O)(O)O

nearest known ligand 0.52

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.52
MMP2 P08253 3/20 0.48
MMP1 P03956 2/20 0.48
MMP3 P08254 1/20 0.48
MMP9 P14780 1/20 0.48
S1PR2 O95136 7/20 0.46
S1PR1 P21453 7/20 0.46
S1PR3 Q99500 7/20 0.46
S1PR4 O95977 6/20 0.46
S1PR5 Q9H228 1/20 0.46
PAOX Q6QHF9 1/20 0.44
ADH1B P00325 1/20 0.39
ADH1A P07327 1/20 0.39
ADH7 P40394 1/20 0.39
SAT1 P21673 1/20 0.38
ERAP2 Q6P179 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
FDPS P14324 2/20 0.36
LPAR3 Q9UBY5 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL128359 0.97 ANPEP (0.54) ANPEPMMP2MMP1MMP3MMP9
Phosphoric Acid SCHEMBL128360 0.97 ANPEP (0.54) ANPEPMMP2MMP1MMP3MMP9
Phosphoric Acid SCHEMBL27548473 0.87 ANPEP (0.47) ANPEPMMP2MMP1MMP3MMP9
Phosphoric Acid SCHEMBL14782467 0.85 ANPEP (0.50) ANPEPMMP2MMP1MMP3MMP9
SCHEMBL5595395 0.83 S1PR2 (0.59) ANPEPMMP2MMP1MMP3MMP9
Hydrochloric Acid SCHEMBL5985877 0.81 S1PR2 (0.57) ANPEPMMP2MMP1MMP3MMP9
Ammonia Solution, Strong SCHEMBL4463551 0.80
Phosphoric Acid SCHEMBL2776516 0.80 S1PR2 (0.61) ANPEPMMP2MMP1S1PR2S1PR1
Phosphoric Acid SCHEMBL2776513 0.80 S1PR2 (0.61) ANPEPMMP2MMP1S1PR2S1PR1
SCHEMBL16713982 0.79 ANPEP (0.45) ANPEPMMP2MMP1MMP3MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111317674-A Hair care conditioning composition 上海兴博隆精细化工有限公司 2020-06-23 CN disclosed