Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17902915 | 0.87 | YTHDC1 (0.71) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL28433352 | 0.87 | YTHDC1 (0.74) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL20104998 | 0.85 | YTHDC1 (0.72) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL16549246 | 0.85 | YTHDC1 (0.69) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL17929775 | 0.84 | YTHDC1 (0.70) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL17902904 | 0.83 | YTHDC1 (0.72) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL5695023 | 0.82 | YTHDC1 (0.65) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL16549233 | 0.82 | YTHDC1 (0.68) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL29206263 | 0.82 | YTHDC1 (0.67) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL20547443 | 0.82 | YTHDC1 (0.62) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111377925-A | Purine derivative, preparation method and medical application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-07-07 | — | — | CN | disclosed |