Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 4/20 | 0.45 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 4/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.34 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28420718 | 0.91 | TEAD1 (0.40) | TEAD1TEAD3FGFR1FGFR2FGFR3 | |
| SCHEMBL17085551 | 0.82 | TEAD1 (0.49) | TEAD1TEAD3BTKJAK3JAK2 | |
| SCHEMBL23277543 | 0.81 | EPHX2 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL29265199 | 0.78 | EPHX2 (0.42) | ALDH1A1 | |
| SCHEMBL16285101 | 0.78 | TEAD1 (0.49) | TEAD1TEAD3FGFR1FGFR2FGFR3 | |
| SCHEMBL29265195 | 0.77 | MAPT (0.48) | ALDH1A1KMT2A | |
| SCHEMBL25207977 | 0.76 | TEAD1 (0.45) | TEAD1TEAD3BTKJAK3JAK2 | |
| SCHEMBL25788054 | 0.76 | TEAD1 (0.45) | TEAD1TEAD3BTKJAK3JAK2 | |
| SCHEMBL17235749 | 0.76 | TEAD1 (0.45) | TEAD1TEAD3FGFR1FGFR2FGFR3 | |
| SCHEMBL16285087 | 0.75 | TEAD1 (0.47) | TEAD1TEAD3FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108295073-B | Polyfluoro compounds as bruton's tyrosine kinase inhibitors | 浙江导明医药科技有限公司 | 2020-06-16 | — | — | CN | disclosed |