Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23277543 | 0.83 | EPHX2 (0.38) | EPHX2ALDH1A1EPHX1 | |
| SCHEMBL4487574 | 0.82 | EPHX2 (0.51) | EPHX2ALDH1A1EPHX1NPC1GNAI3 | |
| SCHEMBL29265195 | 0.79 | MAPT (0.48) | ALDH1A1 | |
| SCHEMBL28429128 | 0.78 | TEAD1 (0.45) | ALDH1A1 | |
| SCHEMBL29201782 | 0.78 | BPTF (0.55) | EPHX2ALDH1A1EPHX1 | |
| SCHEMBL7442420 | 0.77 | GPR119 (0.49) | EPHX1 | |
| SCHEMBL12396094 | 0.76 | EPHX2 (0.46) | EPHX2ALDH1A1EPHX1NPC1GNAI3 | |
| SCHEMBL28381486 | 0.75 | NCF1 (0.43) | ALDH1A1GNAI3GNAO1GNAI1CHRM2 | |
| SCHEMBL16077702 | 0.75 | EPHX2 (0.51) | EPHX2ALDH1A1EPHX1NPC1GNAI3 | |
| SCHEMBL22557067 | 0.74 | EPHX2 (0.42) | EPHX2ALDH1A1EPHX1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113766953-B | N-acyl- {4- [ (4-aryl-phenyl) sulfonylmethyl ] piperidine } compounds and their therapeutic uses | 现代生物科学有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-113766953-A | N-acyl- {4- [ (4-aryl-phenyl) sulfonylmethyl ] piperidine } compounds and their therapeutic use | 现代生物科学有限公司 | 2021-12-07 | — | — | CN | disclosed |