Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25308528 | 1.00 | ESR1 (0.44) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5342890 | 0.89 | ESR1 (0.38) | ESR1ESR2 | |
| SCHEMBL28435698 | 0.87 | GAA (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL721908 | 0.87 | GAA (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7640660 | 0.87 | GAA (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL721803 | 0.87 | GAA (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL720021 | 0.87 | GAA (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2139698 | 0.85 | KDM4E (0.36) | ESR1ESR2 | |
| SCHEMBL30288151 | 0.85 | KDM4E (0.36) | ESR1ESR2 | |
| SCHEMBL28115085 | 0.82 | L3MBTL1 (0.51) | ESR1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107532834-B | Refrigerant circulation device and refrigerant circulation method | 三菱重工制冷空调系统株式会社 | 2020-06-19 | — | — | CN | disclosed |