Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896460 | 0.93 | PPARG (0.70) | PPARGAGTR1KCNH2 | |
| SCHEMBL1893693 | 0.92 | PPARG (0.70) | PPARGAGTR1KCNH2 | |
| SCHEMBL1890861 | 0.88 | PPARG (0.64) | PPARGAGTR1KCNH2 | |
| SCHEMBL1895526 | 0.87 | PPARG (0.63) | PPARGAGTR1KCNH2 | |
| Bromide SCHEMBL1888121 | 0.87 | PPARG (0.63) | PPARGAGTR1KCNH2 | |
| SCHEMBL1892273 | 0.87 | PPARG (0.63) | PPARGAGTR1KCNH2 | |
| SCHEMBL1888993 | 0.85 | PPARG (0.53) | PPARGAGTR1KCNH2 | |
| SCHEMBL1892387 | 0.84 | PPARG (0.53) | PPARGAGTR1KCNH2 | |
| SCHEMBL1892337 | 0.83 | AGTR1 (0.63) | PPARGAGTR1KCNH2 | |
| SCHEMBL1891041 | 0.82 | AGTR1 (0.62) | PPARGAGTR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256115-A1 | Heteromonocyclic compound and use thereof | Takeda Pharmaceutical Company Limited (JP) | 2010-12-01 | — | — | EP | disclosed |