Benzene

Benzene

SCHEMBL28429296

Oc1ccc(S)cc1.c1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA3 P07451 4/20 0.53
CA14 Q9ULX7 4/20 0.53
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA4 P22748 3/20 0.53
CA9 Q16790 3/20 0.53
ALDH1A1 P00352 3/20 0.53
CYP3A4 P08684 3/20 0.53
ALOX15 P16050 3/20 0.53
MEN1 O00255 2/20 0.53
NPC1 O15118 2/20 0.53
KMT2A Q03164 2/20 0.53
TYR P14679 2/20 0.53
CA5A P35218 2/20 0.53
CA5B Q9Y2D0 2/20 0.53
HIF1A Q16665 2/20 0.53
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 1/20 0.53
GMNN O75496 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62871 0.93
Water SCHEMBL28352698 0.90
SCHEMBL11863520 0.90
Methane SCHEMBL506650 0.90
SCHEMBL8217008 0.90
Naphthalene SCHEMBL28954267 0.85 CYP1A2 (0.52) CA3CA14CA12CA1CA2
Chlorobenzene SCHEMBL10877524 0.84 IDO1 (0.55) CA3CA14CA12CA1CA2
Toluene SCHEMBL1057886 0.84 ACHE (0.55) CA3CA14CA12CA1CA2
Phenol SCHEMBL1122819 0.84 CA12 (0.69) CA3CA14CA12CA1CA2
SCHEMBL64905 0.84 ESR1 (0.69) CA3CA14CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111302993-B Preparation method of 4-phenylmercaptothiophenol 新发药业有限公司 2022-10-21 CN disclosed
CN-111302993-A Preparation method of 4-phenylmercaptothiophenol 新发药业有限公司 2020-06-19 CN disclosed
CN-107406392-A Composition of matter and molecular resists made therefrom 亚历克斯·菲利普·格雷厄姆·罗宾逊 2017-11-28 CN disclosed