SCHEMBL28429348

SCHEMBL28429348

C=CC(C)C(=O)NC(C)=O.[SiH4]

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TAS2R38 P59533 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29885983 0.98 CRBN (0.35) CRBNTSHRALDH1A1TAS2R38LMNA
SCHEMBL442561 0.73
SCHEMBL5168501 0.70 CA1 (0.39)
SCHEMBL10942414 0.69 CRBN (0.43) CRBNTSHRALDH1A1TAS2R38LMNA
SCHEMBL3787125 0.69
SCHEMBL2220319 0.69
SCHEMBL16311352 0.68
SCHEMBL18822535 0.68
SCHEMBL11519300 0.68
Hydrochloric Acid SCHEMBL3710252 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111471155-B Silane-terminated modified polyurethane resin, high-strength low-modulus modified polyurethane sealant and preparation method thereof 湖南耐渗塑胶工程材料有限公司 2022-08-30 CN claimed
CN-113861933-A Elastic adhesive and preparation method thereof 北京盈和瑞环境科技有限公司 2021-12-31 CN claimed
CN-108753198-B Adhesion promoter for silicone sealant, preparation method of adhesion promoter, silicone sealant applied to ballastless track and preparation method of silicone sealant 株洲飞鹿高新材料技术股份有限公司 2021-03-02 CN claimed
CN-111471155-A Silane-terminated modified polyurethane resin, high-strength low-modulus modified polyurethane sealant and preparation method thereof 株洲飞鹿高新材料技术股份有限公司 2020-07-31 CN claimed
CN-113861933-A Elastic adhesive and preparation method thereof 北京盈和瑞环境科技有限公司 2021-12-31 CN disclosed
CN-111471155-A Silane-terminated modified polyurethane resin, high-strength low-modulus modified polyurethane sealant and preparation method thereof 株洲飞鹿高新材料技术股份有限公司 2020-07-31 CN disclosed