⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15830379 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL29885983 | 0.75 | CRBN (0.35) | — | |
| SCHEMBL11519300 | 0.73 | — | — | |
| SCHEMBL16311352 | 0.73 | — | — | |
| SCHEMBL28429348 | 0.73 | CRBN (0.33) | — | |
| SCHEMBL18822535 | 0.73 | — | — | |
| SCHEMBL20537347 | 0.72 | TSHR (0.35) | — | |
| SCHEMBL10269359 | 0.72 | — | — | |
| SCHEMBL22521047 | 0.72 | — | — | |
| SCHEMBL15833977 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103946325-B | Aqueous coating compositions | 湛新奥地利有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-109689714-B | Silicone hydrogels comprising N-alkylmethacrylamides and contact lenses made therefrom | 庄臣及庄臣视力保护公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-109415474-B | Silicone hydrogels comprising high levels of polyamides | 庄臣及庄臣视力保护公司 | 2022-05-10 | — | — | CN | disclosed |
| EP-3818129-A1 | PROGRESSIVE SALTING-OUT OF POLYMER CHAINS IN A LIQUID MEDIUM | RHODIA OPERATIONS (FR) | 2021-05-12 | — | — | EP | disclosed |
| WO-2020007828-A1 | PROGRESSIVE SALTING-OUT OF POLYMER CHAINS IN A LIQUID MEDIUM | RHODIA OPERATIONS (FR) | 2020-01-09 | — | — | WO | disclosed |
| EP-3523338-A1 | TRI-BLOCK PREPOLYMERS AND THEIR USE IN SILICONE HYDROGELS | Johnson & Johnson Vision Care Inc. (US) | 2019-08-14 | — | — | EP | disclosed |
| EP-3481897-A1 | SILICONE HYDROGELS COMPRISING POLYAMIDES | Johnson & Johnson Vision Care Inc. (US) | 2019-05-15 | — | — | EP | disclosed |
| WO-2018067284-A1 | TRI-BLOCK PREPOLYMERS AND THEIR USE IN SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2018-04-12 | — | — | WO | disclosed |
| EP-3303506-A1 | AMPHIPHILIC POLYMERS FOR FILTRATE CONTROL | Rhodia Operations (FR) | 2018-04-11 | — | — | EP | disclosed |
| WO-2018009311-A1 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2018-01-11 | — | — | WO | disclosed |
| EP-2260335-A1 | TINTED SILICONE OPHTHALMIC DEVICES, PROCESSES AND POLYMERS USED IN THE PREPARATION OF SAME | Johnson & Johnson Vision Care, Inc. (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2010130763-A2 | PRECIPITATED POLYMERS | BASF SE (DE) | 2010-11-18 | — | — | WO | disclosed |
| WO-2009124048-A1 | TINTED SILICONE OPHTHALMIC DEVICES, PROCESSES AND POLYMERS USED IN THE PREPARATION OF SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2009-10-08 | — | — | WO | disclosed |
| US-20090244479-A1 | TINTED SILICONE OPHTHALMIC DEVICES, PROCESSES AND POLYMERS USED IN THE PREPARATION OF SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2009-10-01 | — | — | US | disclosed |
| EP-1971376-A1 | SILICONE CONTAINING POLYMERS FORMED FROM NON-REACTIVE SILICONE CONTAINING PREPOLYMERS | Johnson and Johnson Vision Care, Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007078871-A1 | SILICONE CONTAINING POLYMERS FORMED FROM NON-REACTIVE SILICONE CONTAINING PREPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| EP-1732961-A1 | POLYMERS COMPRISING DIALLYLAMINES | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005095479-A1 | POLYMERS COMPRISING DIALLYLAMINES | BASF AKTIENGESELLSCHAFT (DE) | 2005-10-13 | — | — | WO | disclosed |
| EP-0958402-A1 | ZINC PHOSPHATING WITH INTEGRATED SUBSEQUENT PASSIVATION | Henkel Kommanditgesellschaft auf Aktien (DE) | 1999-11-24 | — | — | EP | disclosed |
| WO-1997045568-A1 | ZINC PHOSPHATING WITH INTEGRATED SUBSEQUENT PASSIVATION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-12-04 | — | — | WO | disclosed |