SCHEMBL28429428

SCHEMBL28429428

O=C(O)c1c(O)ccc(-c2ccccc2)c1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
BACE1 P56817 1/20 0.48
ALOX5 P09917 1/20 0.47
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
BCL2L1 Q07817 1/20 0.46
HSD17B10 Q99714 1/20 0.46
FOLH1 Q04609 1/20 0.46
HNF4A P41235 3/20 0.46
ACMSD Q8TDX5 3/20 0.46
DHFR P00374 1/20 0.46
MCL1 Q07820 1/20 0.46
PTPN1 P18031 1/20 0.43
LMNA P02545 1/20 0.42
HDAC4 P56524 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23521242 0.89 FOLH1 (0.53) CA12CA1CA2CA7CA9
SCHEMBL31095720 0.86 HSD17B10 (0.53) CA12CA1CA2CA7CA9
SCHEMBL29420726 0.86 HSD17B10 (0.53) CA12CA1CA2CA7CA9
SCHEMBL27718034 0.86 HNF4A (0.53) CA12CA1CA2CA7CA9
SCHEMBL5590480 0.86 HNF4A (0.48) CA12CA1CA2CA7CA9
SCHEMBL21879681 0.85 CDC25B (0.50) ALDH1A1HPGDBCL2L1FOLH1HNF4A
SCHEMBL11900978 0.84 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL8747589 0.84 CA12 (0.48) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL27739302 0.84 HNF4A (0.52) CA12CA1CA2CA7CA9
SCHEMBL3264678 0.83 CA12 (0.64) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111359668-A Preparation method of metal organic framework single-site catalyst for simulating peroxidase 浙江大学 2020-07-03 CN claimed
CN-111359668-A Preparation method of metal organic framework single-site catalyst for simulating peroxidase 浙江大学 2020-07-03 CN disclosed