Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.36 |
| ▸ | JAK1 | P23458 | 4/20 | 0.36 |
| ▸ | JAK3 | P52333 | 4/20 | 0.36 |
| ▸ | TYK2 | P29597 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Propyl Bromide SCHEMBL27530289 | 0.92 | JAK2 (0.35) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL27694314 | 0.85 | JAK2 (0.42) | JAK2JAK1JAK3TYK2 | |
| Ammonia Solution, Strong SCHEMBL29186840 | 0.85 | — | — | |
| Bromide SCHEMBL28991986 | 0.85 | — | — | |
| Formaldehyde SCHEMBL7383866 | 0.81 | JAK2 (0.42) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL4718556 | 0.79 | JAK2 (0.38) | JAK2JAK1JAK3TYK2 | |
| 1-Pentanol SCHEMBL27569497 | 0.79 | SMN1; SMN2 (0.39) | JAK2JAK1JAK3TYK2 | |
| 1,3-Propanediol SCHEMBL15299981 | 0.78 | JAK2 (0.36) | JAK2JAK1JAK3TYK2 | |
| Hydrochloric Acid SCHEMBL27486715 | 0.77 | KDM4E (0.35) | — | |
| SCHEMBL27526857 | 0.76 | JAK2 (0.34) | JAK2JAK1JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471056-B | Macrocyclic immunomodulator | 成都先导药物开发股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-111471056-A | Macrocyclic immunomodulator | 成都先导药物开发股份有限公司 | 2020-07-31 | — | — | CN | disclosed |