Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL29186840 | 0.95 | — | — | |
| Formaldehyde SCHEMBL7383866 | 0.91 | JAK2 (0.42) | — | |
| SCHEMBL27694314 | 0.91 | JAK2 (0.42) | — | |
| SCHEMBL4718556 | 0.89 | JAK2 (0.38) | — | |
| Bromoethane SCHEMBL28429545 | 0.85 | JAK2 (0.36) | — | |
| 1,3-Propanediol SCHEMBL15299981 | 0.83 | JAK2 (0.36) | — | |
| N-Propyl Bromide SCHEMBL27530289 | 0.82 | JAK2 (0.35) | — | |
| SCHEMBL27526857 | 0.80 | JAK2 (0.34) | — | |
| SCHEMBL7921876 | 0.79 | JAK2 (0.36) | — | |
| N-Methylpiperidine SCHEMBL27486716 | 0.78 | JAK2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055927-A | Substituted phenylpropionic acid derivative and application thereof | 上海拓界生物医药科技有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-114057770-B | Bifunctional compounds targeting EGFR protein degradation | 成都先导药物开发股份有限公司 | 2023-05-02 | — | — | CN | disclosed |