Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20400973 | 1.00 | CA12 (0.41) | CA12CA1CA2CA9ACE | |
| SCHEMBL3721142 | 0.94 | ACE (0.44) | CA12CA1CA2CA9ACE | |
| SCHEMBL3739768 | 0.94 | ACE (0.44) | CA12CA1CA2CA9ACE | |
| SCHEMBL1524224 | 0.94 | ACE (0.44) | CA12CA1CA2CA9ACE | |
| SCHEMBL28432499 | 0.85 | ATM (0.32) | ACE | |
| SCHEMBL20401099 | 0.85 | ATM (0.32) | ACE | |
| SCHEMBL1950731 | 0.83 | ACE (0.50) | ACE | |
| SCHEMBL6478173 | 0.83 | ACE (0.50) | ACE | |
| SCHEMBL258790 | 0.83 | ACE (0.50) | ACE | |
| SCHEMBL23247452 | 0.81 | CA12 (0.37) | CA12CA1CA2CA9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356456-A | 2-arylsulfonamido-iV-arylacetamide derived Stat3 inhibitor | 夏威夷大学 | 2020-06-30 | — | — | CN | disclosed |