SCHEMBL6478173

SCHEMBL6478173

O=C(O)[C@@H]1CCCCN1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACE P12821 7/20 0.50
REN P00797 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1950731 1.00 ACE (0.50) ACEREN
SCHEMBL258790 1.00 ACE (0.50) ACEREN
SCHEMBL3791081 0.98 ACE (0.49) ACE
SCHEMBL21874335 0.98 ACE (0.49) ACE
SCHEMBL27957044 0.98 ACE (0.49) ACE
SCHEMBL750903 0.93 ACE (0.56) ACEREN
SCHEMBL1543546 0.93 ACE (0.56) ACEREN
SCHEMBL187408 0.93 ACE (0.56) ACEREN
Bromide SCHEMBL6544002 0.91 ACE (0.55) ACEREN
Ammonia Solution, Strong SCHEMBL29036066 0.91 ACE (0.55) ACEREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667539-A Translation system with altered genetic code tables 中外制药株式会社 2023-01-31 CN disclosed
CN-113423877-A Mutant tRNAs for codon expansion 中外制药株式会社 2021-09-21 CN disclosed
WO-2021117848-A1 METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID 中外製薬株式会社 2021-06-17 WO disclosed
EP-3716981-A1 COMPOUNDS FOR TREATING NEAR VISION DISORDERS Viewpoint Therapeutics, Inc. (US) 2020-10-07 EP disclosed
WO-2005007162-A1 COMPOUNDS AUGMENTING THE ACTIVITY OF ANTIBACTERIAL AGENTS VERTEX PHARMACEUTICALS INCORPORATED (US) 2005-01-27 WO disclosed
CN-1168443-C Methods and compsns. for stimulating neurite growth using compounds with affinity for FKBP12 in combination with neurotrophic factors ��̩��˹ҩ��ɷ����޹�˾ 2004-09-29 CN disclosed
CN-1494906-A Application of compound in preparation of medicine for preventing and curing multiple drug resistance ��̩��˹ҩ��ɷ����޹�˾ 2004-05-12 CN disclosed
CN-1239435-A Methods and compsns. for stimulating neurite growth using compounds with affinity for FKBP12 in combination with neurotrophic factors VERTEX PHARMA (US) 1999-12-22 CN disclosed
CN-1239434-A Methods and compsns. for stimulating neurite growth using compounds with affinity for FKBP12 in combination with neurotrophic factors VERTED PHARMACEUTICALS INC (US) 1999-12-22 CN disclosed
EP-0941113-A1 METHODS AND COMPOSITIONS FOR STIMULATING NEURITE GROWTH USING COMPOUNDS WITH AFFINITY FOR FKBP12 IN COMBINATION WITH NEUROTROPHIC FACTORS Vertex Pharmaceuticals Incorporated (US) 1999-09-15 EP disclosed
WO-1998020893-A1 METHODS AND COMPOSITIONS FOR STIMULATING NEURITE GROWTH USING COMPOUNDS WITH AFFINITY FOR FKBP12 IN COMBINATION WITH NEUROTROPHIC FACTORS VERTEX PHARMACEUTICALS INCORPORATED (US) 1998-05-22 WO disclosed
US-5723459-A IMMUNOSUPPRESSANTS FOR MULTIDRUG RESISTANCE VERTEX PHARMACEUTICALS INCORPORATED (US) 1998-03-03 US disclosed
US-5620971-A Biologically active acylated amino acid derivatives VERTEX PHARMACEUTICALS INCORPORATED (US) 1997-04-15 US disclosed
EP-0662958-A1 1-(2-OXO-ACETYL)-PIPERIDINE-2-CARBOXYLIC ACID DERIVATIVES AS MULTI-DRUG-RESISTENT CANCER CELL SENSITIZERS VERTEX PHARMACEUTICALS INCORPORATED (US) 1995-07-19 EP disclosed
WO-1994007858-A1 1-(2-OXO-ACETYL)-PIPERIDINE-2-CARBOXYLIC ACID DERIVATIVES AS MULTI-DRUG-RESISTENT CANCER CELL SENSITIZERS VERTEX PHARMACEUTICALS INCORPORATED (US) 1994-04-14 WO disclosed
WO-1993001174-A1 THIAZOLIDINE DERIVATIVES AND THEIR USE AS ANTI-VIRAL COMPOUNDS GLAXO GROUP LIMITED (GB) 1993-01-21 WO disclosed