Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10216743 | 0.85 | FAAH (0.44) | FAAHALDH1A1POLBKDM4EGAA | |
| SCHEMBL20792320 | 0.84 | FAAH (0.45) | FAAHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL10216747 | 0.84 | FAAH (0.44) | FAAHPOLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10217058 | 0.84 | HDAC1 (0.46) | FAAHPOLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22321391 | 0.83 | KCNQ3 (0.50) | FAAHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL13168015 | 0.83 | KCNQ3 (0.50) | FAAHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL10216833 | 0.83 | KCNQ3 (0.50) | FAAHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL10217061 | 0.83 | HDAC1 (0.45) | FAAHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL10216752 | 0.83 | PTPRB (0.45) | FAAHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL10217045 | 0.83 | FAAH (0.45) | FAAHALDH1A1POLBGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372928-B | Benzimidazole derivatives as potassium channel inhibitors | 阿塞西翁制药公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-111372928-A | Benzimidazole derivatives as potassium channel inhibitors | 阿塞西翁制药公司 | 2020-07-03 | — | — | CN | disclosed |