Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | TPMT | P51580 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29759213 | 0.82 | HCAR1 (0.59) | HCAR1CES2CES1HCAR2POLB | |
| SCHEMBL560207 | 0.82 | HCAR1 (0.59) | HCAR1CES2CES1HCAR2POLB | |
| SCHEMBL22400614 | 0.81 | NOTUM (0.50) | CES2CES1POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5226036 | 0.80 | HCAR1 (0.57) | HCAR1CES2CES1HCAR2POLB | |
| SCHEMBL8271150 | 0.77 | IDO1 (0.43) | CES2CES1CA1CA2CA9 | |
| SCHEMBL22400377 | 0.77 | TTR (0.35) | HCAR1CES2CES1HCAR2POLB | |
| SCHEMBL29639672 | 0.77 | DAO (0.44) | HCAR1HCAR2POLBTTRPPARA | |
| SCHEMBL31408177 | 0.75 | CA1 (0.46) | TTRSRD5A2CA1CA2CA9 | |
| SCHEMBL3067961 | 0.75 | POLB (0.38) | HCAR1HCAR2POLBTTRSRD5A2 | |
| SCHEMBL3067954 | 0.75 | POLB (0.38) | HCAR1HCAR2POLBTTRSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624207-A | Glucose-sensitive albumin binding derivatives | 诺和诺德股份有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-111315751-B | Glucose-sensitive albumin binding derivatives | 诺和诺德股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-111315751-A | Glucose-sensitive albumin binding derivatives | 诺沃挪第克公司 | 2020-06-19 | — | — | CN | disclosed |