SCHEMBL28429987

SCHEMBL28429987

CC(C)(C)OC(=O)N1CCc2cc(C3CC3)ccc21

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 7/20 0.50
TRIM24 O15164 6/20 0.49
BRPF1 P55201 1/20 0.48
DHODH Q02127 1/20 0.43
HRH3 Q9Y5N1 2/20 0.43
NAMPT P43490 1/20 0.42
NOTUM Q6P988 1/20 0.42
ABHD6 Q9BV23 1/20 0.42
BRD4 O60885 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30681488 1.00 GPR119 (0.50) GPR119TRIM24BRPF1DHODHHRH3
SCHEMBL30681529 0.95 GPR119 (0.48) GPR119TRIM24BRPF1DHODHHRH3
SCHEMBL30681257 0.92 GPR119 (0.46) GPR119TRIM24BRPF1DHODHNAMPT
SCHEMBL30681459 0.90 CHRM4 (0.48) GPR119TRIM24BRPF1HRH3NAMPT
SCHEMBL10447445 0.90 CHRM4 (0.48) GPR119TRIM24BRPF1HRH3NAMPT
SCHEMBL30681277 0.89 GPR119 (0.46) GPR119TRIM24BRPF1DHODHNOTUM
SCHEMBL30681412 0.89 GPR119 (0.47) GPR119TRIM24DHODHNOTUMABHD6
SCHEMBL31599439 0.87 GPR119 (0.45) GPR119TRIM24BRPF1DHODHABHD6
SCHEMBL30681360 0.85 CHRM4 (0.47) GPR119TRIM24HRH3NAMPTNOTUM
SCHEMBL30681369 0.82 CHRM4 (0.45) GPR119TRIM24NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171420-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME MONTE ROSA THERAPEUTICS AG (CH) 2025-05-29 US disclosed
CN-111471037-B Allylamine compound and application thereof 药捷安康(南京)科技股份有限公司 2023-02-10 CN disclosed
CN-111471037-A Allylamine compound and application thereof 南京药捷安康生物科技有限公司 2020-07-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171420-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME PSMA1, CSNK1G1, CSNK1A1 GPR119 4453/4885TRIM24 738/4885BRPF1 2325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.