Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199629 | 0.74 | TDP1 (0.50) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL19264965 | 0.72 | TDP1 (0.45) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL20400430 | 0.71 | NPC1 (0.45) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL20400910 | 0.70 | TDP1 (0.46) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL20400887 | 0.70 | TDP1 (0.46) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL25166327 | 0.70 | TDP1 (0.40) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL30469661 | 0.69 | TDP1 (0.53) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL24366369 | 0.69 | TDP1 (0.53) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL16626827 | 0.68 | HCAR3 (0.44) | RAB9ACYP3A4PDGFRBPDGFRA | |
| SCHEMBL20400543 | 0.66 | MAPK1 (0.41) | TDP1NPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356456-A | 2-arylsulfonamido-iV-arylacetamide derived Stat3 inhibitor | 夏威夷大学 | 2020-06-30 | — | — | CN | disclosed |