Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872013 | 0.98 | LMNA (0.50) | LMNASMN1; SMN2OPRM1ALDH1A1MEN1 | |
| SCHEMBL7875772 | 0.98 | LMNA (0.50) | LMNASMN1; SMN2OPRM1ALDH1A1MEN1 | |
| SCHEMBL7875780 | 0.98 | LMNA (0.50) | LMNASMN1; SMN2OPRM1ALDH1A1MEN1 | |
| SCHEMBL7870878 | 0.98 | LMNA (0.50) | LMNASMN1; SMN2OPRM1ALDH1A1MEN1 | |
| Ethylene Glycol SCHEMBL9296590 | 0.95 | LMNA (0.46) | LMNASMN1; SMN2OPRM1ALDH1A1MEN1 | |
| SCHEMBL7943946 | 0.95 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2OPRM1ALDH1A1MEN1 | |
| Ethylene Glycol SCHEMBL23391391 | 0.93 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| Ethylene Glycol SCHEMBL28556296 | 0.93 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| Ethylene Glycol SCHEMBL23391403 | 0.93 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| Ethylene Glycol SCHEMBL4353876 | 0.93 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372985-A | Spike-free antiskid tread rubber composition for winter tire | 住友橡胶工业株式会社 | 2020-07-03 | — | — | CN | disclosed |