Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 6/20 | 0.39 |
| ▸ | BCR | P11274 | 6/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28434919 | 0.93 | PLA2G2D (0.41) | NPC1RAB9AABL1BCRG6PD | |
| SCHEMBL16719868 | 0.93 | NPC1 (0.51) | NPC1RAB9AGRM5ABL1BCR | |
| SCHEMBL16720569 | 0.85 | NPC1 (0.46) | NPC1RAB9AABL1BCRG6PD | |
| SCHEMBL28431013 | 0.83 | ABL1 (0.39) | NPC1RAB9AGRM5ABL1BCR | |
| SCHEMBL28434917 | 0.78 | ABL1 (0.39) | NPC1RAB9AABL1BCRLCK | |
| SCHEMBL16720332 | 0.77 | NPC1 (0.62) | NPC1RAB9AG6PDCASP7CASP6 | |
| SCHEMBL16720280 | 0.77 | G6PD (0.47) | NPC1RAB9AGRM5G6PDCASP7 | |
| SCHEMBL16719792 | 0.75 | NPC1 (0.46) | NPC1RAB9AGRM5PARP1SLC16A3 | |
| SCHEMBL16719361 | 0.74 | GRM5 (0.55) | GRM5PARP1 | |
| Trifluoroacetic Acid SCHEMBL10277552 | 0.74 | GSK3B (0.50) | GRM5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105934425-B | EBNA1 inhibitors and methods of use thereof | 威斯塔解剖学和生物学研究所 | 2020-08-07 | — | — | CN | disclosed |