Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21358600 | 0.84 | NFE2L2 (0.37) | CYP1A2SMN1; SMN2NFE2L2METAP1EPHX1 | |
| SCHEMBL13500027 | 0.83 | CYP1A2 (0.41) | HSD17B10CYP1A2SMN1; SMN2NFE2L2METAP2 | |
| SCHEMBL13459004 | 0.79 | USP2 (0.46) | CYP1A2SMN1; SMN2NFE2L2METAP1EPHX1 | |
| SCHEMBL25867721 | 0.78 | SPHK2 (0.37) | CYP1A2NFE2L2 | |
| SCHEMBL18022770 | 0.77 | HSD17B10 (0.47) | HSD17B10TDP1MAPK1EPHX1 | |
| SCHEMBL8743871 | 0.76 | CYP1A2 (0.46) | HSD17B10CYP1A2SMN1; SMN2NFE2L2MEN1 | |
| SCHEMBL11224710 | 0.76 | CYP1A2 (0.46) | HSD17B10CYP1A2SMN1; SMN2NFE2L2MEN1 | |
| SCHEMBL6129979 | 0.76 | CYP1A2 (0.40) | CYP1A2SMN1; SMN2NFE2L2METAP2MEN1 | |
| SCHEMBL18537061 | 0.74 | CYP1A2 (0.39) | CYP1A2SMN1; SMN2NFE2L2METAP2METAP1 | |
| SCHEMBL8588419 | 0.74 | HSD17B10 (0.44) | HSD17B10TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111050571-A | Foam control | 陶氏环球技术有限责任公司 | 2020-04-21 | — | — | CN | disclosed |