SCHEMBL28432969

SCHEMBL28432969

COC(=O)c1ccccc1OBr

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.63
HTT P42858 1/20 0.63
SLC6A3 Q01959 4/20 0.62
TSHR P16473 2/20 0.59
LMNA P02545 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.57
HSD17B10 Q99714 2/20 0.57
ALDH1A1 P00352 1/20 0.57
CFTR P13569 1/20 0.57
SLC6A4 P31645 2/20 0.56
ATM Q13315 2/20 0.55
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.55
MAPT P10636 3/20 0.53
GAA P10253 1/20 0.53
MAPK1 P28482 1/20 0.53
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA5A P35218 1/20 0.50
CA9 Q16790 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl 2-Methoxybenzoate SCHEMBL29702077 0.85 TSHR (0.69) KMT2AHTTSLC6A3TSHRLMNA
SCHEMBL2441955 0.85 SLC6A3 (0.65) KMT2AHTTSLC6A3TSHRLMNA
Methyl 2-Methoxybenzoate SCHEMBL196037 0.85 TSHR (0.69) KMT2AHTTSLC6A3TSHRLMNA
Methyl 2-Methoxybenzoate SCHEMBL30744939 0.83 MAPT (0.67) KMT2AHTTSLC6A3TSHRLMNA
SCHEMBL4199247 0.83 SLC6A3 (0.62) KMT2AHTTSLC6A3TSHRLMNA
SCHEMBL28176283 0.83 SLC6A3 (0.62) KMT2AHTTSLC6A3TSHRLMNA
SCHEMBL8201911 0.82 SLC6A3 (0.57) KMT2AHTTSLC6A3TSHRLMNA
Dimethyl Phthalate SCHEMBL29669976 0.82 TSHR (0.74) KMT2ASLC6A3TSHRLMNAHSD17B10
Dimethyl Phthalate SCHEMBL29500970 0.82 TSHR (0.74) KMT2ASLC6A3TSHRLMNAHSD17B10
Dimethyl Phthalate SCHEMBL34630 0.82 TSHR (0.74) KMT2ASLC6A3TSHRLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997223-B Preparation method of 5- (4-bromophenyl) -4, 6-dichloropyrimidine 浙江先锋科技股份有限公司 2020-06-30 CN claimed
CN-108997223-B Preparation method of 5- (4-bromophenyl) -4, 6-dichloropyrimidine 浙江先锋科技股份有限公司 2020-06-30 CN disclosed