Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23752124 | 0.77 | HDAC6 (0.46) | HDAC6HDAC1HDAC2DPP4 | |
| SCHEMBL4565939 | 0.75 | — | — | |
| SCHEMBL1810981 | 0.74 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DPP4 | |
| SCHEMBL2622073 | 0.69 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DPP4 | |
| SCHEMBL956549 | 0.69 | ALDH1A1 (0.42) | HDAC6HDAC1HDAC2DPP4 | |
| SCHEMBL17995253 | 0.69 | HDAC6 (0.46) | HDAC6HDAC1HDAC2ELANE | |
| SCHEMBL2754735 | 0.68 | HDAC6 (0.37) | HDAC6HDAC1HDAC2DPP4 | |
| SCHEMBL17162509 | 0.68 | HDAC6 (0.37) | HDAC6HDAC1HDAC2DPP4 | |
| SCHEMBL372321 | 0.67 | SMN1; SMN2 (0.40) | HDAC6HDAC1HDAC2ELANE | |
| SCHEMBL22604686 | 0.67 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315747-B | Dihydropyrazolopyrimidine compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-111315747-A | Dihydropyrazolone pyrimidine compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-06-19 | — | — | CN | disclosed |