Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | CES2 | O00748 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341980 | 0.86 | CES1 (0.46) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL6698945 | 0.86 | CES1 (0.46) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL6692163 | 0.82 | AKR1C1 (0.45) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL9224136 | 0.82 | FASN (0.45) | LMNACES1CES2ALDH1A1TSHR | |
| Benzene SCHEMBL29067363 | 0.80 | HDAC4 (0.46) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL6695613 | 0.80 | HDAC4 (0.46) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL28231289 | 0.80 | HDAC4 (0.46) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL27279 | 0.80 | HDAC4 (0.46) | LMNACES1CES2ALDH1A1TSHR | |
| Water SCHEMBL29044078 | 0.79 | HDAC4 (0.44) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL30936941 | 0.77 | LMNA (0.56) | LMNACES1CES2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115475538-A | Hollow fiber composite nanofiltration membrane based on COFs intermediate layer and preparation method thereof | 中国海洋大学 | 2022-12-16 | — | — | CN | claimed |
| CN-109261128-B | Boric acid type magnetic COFs material, preparation method and application thereof | 西北大学 | 2021-11-02 | — | — | CN | claimed |
| CN-111333852-A | Covalent organic framework material based on quinone group, preparation method and application thereof | 吉林大学 | 2020-06-26 | — | — | CN | claimed |
| CN-113929921-B | Covalent organic framework material with sulfydryl functionalized beta-keto enamine structure and preparation method and application thereof | 青岛理工大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113976049-B | COF/CS aerogel and preparation method and application thereof | 中国地质大学（武汉） | 2022-11-04 | — | — | CN | disclosed |
| CN-114894941-A | Integrated extraction device for separating and ionizing zearalenone toxins and application | 中国检验检疫科学研究院 | 2022-08-12 | — | — | CN | disclosed |
| CN-114636751-A | Integrated mass spectrum ionization device for separating and ionizing zearalenone toxins and application | 中国检验检疫科学研究院 | 2022-06-17 | — | — | CN | disclosed |
| CN-113929921-A | Covalent organic framework material with sulfydryl functionalized beta-keto enamine structure and preparation method and application thereof | 青岛理工大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-109261128-B | Boric acid type magnetic COFs material, preparation method and application thereof | 西北大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-110227357-B | Flexible tailorable nanocellulose/covalent organic framework composite membrane and preparation method thereof | 华南理工大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-111333852-A | Covalent organic framework material based on quinone group, preparation method and application thereof | 吉林大学 | 2020-06-26 | — | — | CN | disclosed |