Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836484 | 0.92 | MAPT (0.32) | USP30 | |
| SCHEMBL4351800 | 0.88 | CYP1A2 (0.34) | USP30SCD5 | |
| SCHEMBL2726470 | 0.87 | NPC1 (0.35) | — | |
| SCHEMBL211341 | 0.87 | USP30 (0.37) | USP30SCD5 | |
| SCHEMBL211340 | 0.87 | USP30 (0.37) | USP30SCD5 | |
| SCHEMBL2725331 | 0.86 | MC4R (0.30) | — | |
| SCHEMBL210306 | 0.85 | HTR2C (0.31) | — | |
| SCHEMBL210305 | 0.85 | HTR2C (0.31) | — | |
| SCHEMBL210307 | 0.85 | HTR2C (0.31) | — | |
| SCHEMBL2836588 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195328-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Incorporated (US) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009023193-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |