Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355654 | 0.92 | MAPT (0.34) | MAPTUSP30EPHX2 | |
| SCHEMBL2843348 | 0.92 | USP30 (0.31) | USP30 | |
| SCHEMBL2841098 | 0.90 | EPHX2 (0.31) | USP30EPHX2 | |
| SCHEMBL4343016 | 0.88 | MAPT (0.37) | MAPTUSP30 | |
| SCHEMBL2725335 | 0.88 | CHRM3 (0.33) | MAPTUSP30EPHX2 | |
| SCHEMBL214458 | 0.87 | GPR119 (0.34) | MAPT | |
| SCHEMBL210350 | 0.87 | GPR119 (0.34) | MAPT | |
| SCHEMBL2725975 | 0.87 | MAPT (0.32) | MAPTUSP30EPHX2 | |
| SCHEMBL212258 | 0.86 | EPHX2 (0.32) | MAPTUSP30EPHX2 | |
| SCHEMBL212260 | 0.86 | EPHX2 (0.32) | MAPTUSP30EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195328-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Incorporated (US) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009023193-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |