Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.56 |
| ▸ | HTR2A | P28223 | 5/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16079468 | 0.82 | HTR6 (0.60) | HTR6HTR2AHTR2CKDM4EUBE2N | |
| SCHEMBL26378166 | 0.82 | HTR6 (0.60) | HTR6HTR2AHTR2CL3MBTL1MEN1 | |
| SCHEMBL28441278 | 0.81 | KDM4E (0.63) | HTR6HTR2AHTR2CKDM4EUBE2N | |
| SCHEMBL17422026 | 0.80 | HTR6 (0.69) | HTR6HTR2AHTR2CKDM4EUBE2N | |
| SCHEMBL3678959 | 0.80 | CA1 (0.51) | HTR6HTR2AHTR2CKDM4EUBE2N | |
| SCHEMBL31315855 | 0.80 | KDM4E (0.50) | HTR6HTR2AHTR2CKDM4EUBE2N | |
| SCHEMBL18690957 | 0.79 | HTR6 (0.62) | HTR6HTR2AHTR2CKDM4EUBE2N | |
| SCHEMBL28440054 | 0.76 | KDM4E (0.49) | HTR6HTR2AHTR2CKDM4EUBE2N | |
| SCHEMBL13378914 | 0.75 | HTR6 (0.51) | HTR6HTR2AHTR2CHTR1DHTR1B | |
| SCHEMBL30958262 | 0.75 | HTR6 (0.53) | HTR6HTR2AHTR2CKDM4EUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081807-B | Method for preparing tri-substituted 4-aminocarbazole and di-substituted 1-aminodibenzo [ b, d ] thiophene compounds | 台州学院 | 2020-08-04 | — | — | CN | disclosed |