Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.63 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.63 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 3/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.58 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30494272 | 1.00 | GLA (0.78) | GLACYSLTR2CYSLTR1TUBB1NPC1 | |
| SCHEMBL28433887 | 1.00 | GLA (0.78) | GLACYSLTR2CYSLTR1TUBB1NPC1 | |
| SCHEMBL11062170 | 0.90 | GLA (0.78) | GLACYSLTR2CYSLTR1NPC1MEN1 | |
| SCHEMBL10036065 | 0.90 | GLA (0.78) | GLACYSLTR2CYSLTR1NPC1MEN1 | |
| SCHEMBL30442596 | 0.88 | GLA (1.00) | GLACYSLTR2CYSLTR1NPC1MEN1 | |
| SCHEMBL29021873 | 0.88 | GLA (1.00) | GLACYSLTR2CYSLTR1NPC1MEN1 | |
| SCHEMBL10680162 | 0.84 | GLA (0.70) | GLACYSLTR2CYSLTR1NPC1MEN1 | |
| SCHEMBL12866125 | 0.83 | RAB9A (0.69) | GLACYSLTR2CYSLTR1NPC1MEN1 | |
| SCHEMBL3860498 | 0.83 | RAB9A (0.69) | GLACYSLTR2CYSLTR1NPC1MEN1 | |
| SCHEMBL8854403 | 0.81 | GLA (0.81) | GLACYSLTR2CYSLTR1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111494381-B | Application of alkenyl quinoline compound in preparation of antitumor drugs | 南方医科大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-111494381-A | Application of alkenyl quinoline compound in preparation of antitumor drugs | 南方医科大学 | 2020-08-07 | — | — | CN | disclosed |