Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.71 |
| ▸ | RET | P07949 | 7/20 | 0.71 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.71 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.71 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.71 |
| ▸ | KIT | P10721 | 3/20 | 0.71 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.71 |
| ▸ | FLT1 | P17948 | 3/20 | 0.71 |
| ▸ | FLT4 | P35916 | 3/20 | 0.71 |
| ▸ | ABL1 | P00519 | 3/20 | 0.71 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.71 |
| ▸ | STK10 | O94804 | 2/20 | 0.71 |
| ▸ | BCR | P11274 | 2/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.71 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.71 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.71 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.71 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.71 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.71 |
| ▸ | ERN1 | O75460 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26726698 | 0.90 | KDR (0.73) | KDRRETAURKBPDGFRAPDGFRB | |
| SCHEMBL23366513 | 0.89 | KDR (0.83) | KDRRETAURKBPDGFRAPDGFRB | |
| SCHEMBL1890089 | 0.89 | KDR (0.77) | KDRRETAURKBPDGFRAPDGFRB | |
| SCHEMBL19072630 | 0.89 | KDR (0.76) | KDRRETAURKBPDGFRAPDGFRB | |
| SCHEMBL2177590 | 0.89 | KDR (0.76) | KDRRETAURKBPDGFRAPDGFRB | |
| SCHEMBL19957067 | 0.88 | KDR (0.75) | KDRRETAURKBPDGFRAPDGFRB | |
| SCHEMBL19957141 | 0.88 | KDR (0.75) | KDRRETAURKBPDGFRAPDGFRB | |
| SCHEMBL28600633 | 0.87 | KDR (0.62) | KDRRETAURKBPDGFRAPDGFRB | |
| SCHEMBL863668 | 0.87 | KDR (0.79) | KDRRETAURKBPDGFRAPDGFRB | |
| SCHEMBL20782693 | 0.87 | KDR (0.69) | KDRRETAURKBPDGFRAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111298127-A | Composition comprising histamine release-promoting substance and inhibitory compound, and oral solid preparation containing the same | 黄泳华 | 2020-06-19 | — | — | CN | claimed |
| CN-111298127-A | Composition comprising histamine release-promoting substance and inhibitory compound, and oral solid preparation containing the same | 黄泳华 | 2020-06-19 | — | — | CN | disclosed |